The Hemoglobinopathy Market Size accounted for USD 5.9 Billion in 2022 and is estimated to achieve a market size of USD 14.3 Billion by 2032 growing at a CAGR of 9.5% from 2023 to 2032.
Hemoglobinopathy Market Highlights
- Global hemoglobinopathy market revenue is poised to garner USD 14.3 billion by 2032 with a CAGR of 9.5% from 2023 to 2032
- North America hemoglobinopathy market value occupied around USD 2.2 billion in 2022
- Asia-Pacific hemoglobinopathy market growth will record a CAGR of more than 11% from 2023 to 2032
- Among type, the thalassemia sub-segment generated over US$ 2.8 billion revenue in 2022
- Based on therapy, the monoclonal antibody medication sub-segment generated around 60% share in 2022
- Rising focus on personalized medicine for better management is a popular hemoglobinopathy market trend that fuels the industry demand
Hemoglobinopathy is a genetic disorder that causes structural abnormalities in hemoglobin molecules. It is a type of hereditary single-gene disease and represents the most common form of sickle cell disease. It is highly prevalent in Africa, South East Asia, and the Mediterranean basin. Critical cases of hemoglobinopathy can lead to anemia, organ dysfunction, or even death if left untreated. Diagnostic tests for the presence of hemoglobinopathies include Gel electrophoresis and complete blood count. Unfortunately, there is no permanent cure for this disease, which has led to an increased demand in the pharmaceutical sector for new product innovations. The high prevalence of the disease, coupled with national control programs in developing economies, drives the need for drug therapy.
Global Hemoglobinopathy Market Dynamics
Market Drivers
- Increasing prevalence in high-risk regions like Africa and South East Asia
- Growing demand for innovative pharmaceutical solutions
- National control programs in developing economies
- Advancements in diagnostic technologies driving early detection
Market Restraints
- Lack of permanent cure options
- Limited accessibility to advanced treatments in certain regions
- Ethical and regulatory challenges in drug development
Market Opportunities
- Research and development for novel therapies
- Collaborative efforts for affordable treatments in underserved areas
- Technological advancements aiding precise diagnostics
Hemoglobinopathy Market Report Coverage
Market |
Hemoglobinopathy Market
|
Hemoglobinopathy Market Size 2022 |
USD 5.9 Billion |
Hemoglobinopathy Market Forecast 2032 |
USD 14.3 Billion |
Hemoglobinopathy Market CAGR During 2023 - 2032 |
9.5% |
Hemoglobinopathy Market Analysis Period |
2020 - 2032 |
Hemoglobinopathy Market Base Year
|
2022 |
Hemoglobinopathy Market Forecast Data |
2023 - 2032 |
Segments Covered |
By Type, By Therapy, By Distribution Channel, And By Geography
|
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and Middle East & Africa |
Key Companies Profiled |
Pfizer, Inc., Bio-Rad Laboratories Inc., Siemens Healthineers, Danaher Corporation, Abbott Diagnostics, PerkinElmer Inc., Nihon Kohden Corporation, Sysmex Corporation, Mindray Medical International Ltd., Nexcelom Bioscience LLC., Sangamo Therapeutics, Inc., and bluebird bio, Inc.
|
Report Coverage
|
Market Trends, Drivers, Restraints, Competitive Analysis, Player Profiling, Covid-19 Analysis, Regulation Analysis |
Hemoglobinopathy Market Insights
Increasing cases of hemoglobinopathy stand as major driving forces for growth, particularly in regions like Southeast Asia and Africa. Approximately 300,000 to 500,000 children are born every year with hemoglobin disorders, according to the World Health Organization (WHO). More than half of these children born with Hb disorders suffer from sickle cell disease (SCD) and thalassemia. Failure to recognize these diseases escalates the death-to-survival ratio for SCD and thalassemia patients. The National Institutes of Health is expected to bolster market growth over the hemoglobinopathy industry forecast period by heightening government and enterprise awareness initiatives for hemoglobin variants, such as the sickle cell initiative launched.
Usual neonatal screening programs serve as effective measures to detect potentially harmful and fatal problems, such as thalassemia and SCD, at an early stage in children, especially in advanced countries. For instance, in 2013, the CDC and the Association of the Laboratories for Public Health partnered on a hemoglobinopathy newborn health screening program under the Division of Blood Disorders. This initiative aimed to assist laboratories in evaluating complications associated with hemoglobinopathies. Additionally, it aimed to provide education on hemoglobinopathy screening programs to caregivers, healthcare workers, and patients.
Another reason for the market's growth is the surge in R&D activities focused on developing new therapeutics. The NHLBI supports SCD research programs aiming to discover novel methods for detecting, treating, and enhancing patient outcomes. Advancements, including gene replacement or editing of the defective SCD gene, along with the transplantation of corrected genes into patients, are underway, leveraging progress in gene-editing technology. Anticipated grants for SCD prevention and treatments are also expected to enhance disease management, following the enactment of the Sickle Cell Disease Research, Surveillance, Prevention, and Treatment Act.
Hemoglobinopathy Market Segmentation
The worldwide market for hemoglobinopathy is split based on type, therapy, distribution channel, and geography.
Hemoglobinopathy Types
- Thalassemia
- Sickle Cell Disease
- Others
Thalassemia's high prevalence and clinical significance make it a prominent player in the hemoglobinopathy market. This genetic blood condition causes aberrant haemoglobin synthesis, which can result in anaemia and other related problems. Its market dominance is greatly influenced by its significance in several places, especially in South Asia, the Mediterranean countries, and parts of Africa. Ongoing research projects focused on creating cutting-edge medication interventions and gene therapies are driving the thalassemia market. The need for diagnostic tools and treatment options is also fueled by increased awareness efforts and proactive screening programmes for carriers and affected persons.
The financial burden of thalassemia highlights the need for ongoing improvements in supporting care and treatment options, as well as the impact it has on patients and their families quality of life. As a result, thalassemia continues to receive a lot of attention in the hemoglobinopathy market, underscoring the necessity of continuing therapeutic advancements and efficient management techniques.
Hemoglobinopathy Therapy
- Monoclonal Antibody Medication
- ACE inhibitors
- Hydroxyurea
- Others
According to hemoglobinopathy industry analysis, the market is dominated by monoclonal antibody medication because of its precise and targeted therapy strategy. By modifying the immune system's reaction and helping to manage hemoglobinopathies such sickle cell disease (SCD), these drugs are designed to attach selectively to certain targets. Their widespread adoption has been fueled by advances in biotechnology and drug research, as well as their effectiveness in targeting specific biochemical pathways linked to certain illnesses. The promise for better patient outcomes and quality of life is what makes monoclonal antibody medication so successful: it can lessen symptoms, lessen problems, and open the door for more individualised and efficient treatment plans.
Hemoglobinopathy Distribution Channels
- Hospital Pharmacy
- Online Providers
- Drug Stores and Retail Pharmacy
Drug stores and retail pharmacies stand out as the major market sector for hemoglobinopathy because of their widespread accessibility and convenience. For patients in need of supportive care items and regular drugs for the treatment of haemoglobin diseases such as thalassemia and sickle cell disease (SCD), these stores are essential hubs.
Their widespread presence in the community and accessibility enable patients to obtain necessary prescription drugs, dietary supplements, and supportive therapies at the earliest opportunity. Furthermore, these establishments frequently provide a wide array of products that address different patient requirements, serving as a one-stop shop for people looking for assistance and remedies for hemoglobinopathies. Improved patient outcomes and illness management are eventually facilitated by this accessibility, which encourages greater adherence to treatment plans.
Hemoglobinopathy Market Regional Outlook
North America
Europe
- U.K.
- Germany
- France
- Spain
- Rest of Europe
Asia-Pacific
- India
- Japan
- China
- Australia
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Mexico
- Rest of Latin America
The Middle East & Africa
- South Africa
- GCC Countries
- Rest of the Middle East & Africa (ME&A)
Hemoglobinopathy Market Regional Analysis
In terms of hemoglobinopathy market analysis, due to increased investment in R&D by major players, improved reimbursement scenarios, and high-quality sanitary infrastructure, North America led the overall revenue market in 2022.
Asia Pacific is expected to experience the fastest growth during the hemoglobinopathy market forecast period. Producers are anticipated to find lucrative growth opportunities in the future with the introduction of indigenous, low-cost diagnostic kits for thalassemia and Sickle-cell disease, alongside increasing patient awareness.
Although hemoglobinopathy incidence is high in underdeveloped economies, including nations in South-East Asia and the Sub-Saharan area, a stronger healthcare system is anticipated to enhance global management of hemoglobinopathies, particularly in advanced markets such as North America and Asia-Pacific. Advanced diagnostics and therapeutics are likely to drive business development in the coming years.
Hemoglobinopathy Market Players
Some of the top hemoglobinopathy companies offered in our report includes Pfizer, Inc., Bio-Rad Laboratories Inc., Siemens Healthineers, Danaher Corporation, Abbott Diagnostics, PerkinElmer Inc., Nihon Kohden Corporation, Sysmex Corporation, Mindray Medical International Ltd., Nexcelom Bioscience LLC., Sangamo Therapeutics, Inc., and bluebird bio, Inc.
CHAPTER 1. Industry Overview of Hemoglobinopathy Market
1.1. Definition and Scope
1.1.1. Definition of Hemoglobinopathy
1.1.2. Market Segmentation
1.1.3. Years Considered for the Study
1.1.4. Assumptions and Acronyms Used
1.1.4.1. Market Assumptions and Market Forecast
1.1.4.2. Acronyms Used in Global Hemoglobinopathy Market
1.2. Summary
1.2.1. Executive Summary
1.2.2. Hemoglobinopathy Market By Type
1.2.3. Hemoglobinopathy Market By Therapy
1.2.4. Hemoglobinopathy Market By Distribution Channel
1.2.5. Hemoglobinopathy Market By Region
CHAPTER 2. Research Approach
2.1. Methodology
2.1.1. Research Programs
2.1.2. Market Size Estimation
2.1.3. Market Breakdown and Data Triangulation
2.2. Data Source
2.2.1. Secondary Sources
2.2.2. Primary Sources
CHAPTER 3. Market Dynamics And Competition Analysis
3.1. Market Drivers
3.1.1. Driver 1
3.1.2. Driver 2
3.2. Restraints and Challenges
3.2.1. Restraint 1
3.2.2. Restraint 2
3.3. Growth Opportunities
3.3.1. Opportunity 1
3.3.2. Opportunity 2
3.4. Porter’s Five Forces Analysis
3.4.1. Bargaining Power of Suppliers
3.4.2. Bargaining Power of Buyers
3.4.3. Threat of Substitute
3.4.4. Threat of New Entrants
3.4.5. Degree of Competition
3.5. Market Concentration Ratio and Market Maturity Analysis of Hemoglobinopathy Market
3.5.1. Go To Market Strategy
3.5.1.1. Introduction
3.5.1.2. Growth
3.5.1.3. Maturity
3.5.1.4. Saturation
3.5.1.5. Possible Development
3.6. Technological Roadmap for Hemoglobinopathy Market
3.7. Value Chain Analysis
3.7.1. List of Key Manufacturers
3.7.2. List of Customers
3.7.3. Level of Integration
3.8. Cost Structure Analysis
3.8.1. Price Trend of Key Raw Materials
3.8.2. Raw Material Suppliers
3.8.3. Proportion of Manufacturing Cost Structure
3.8.3.1. Raw Material
3.8.3.2. Labor Cost
3.8.3.3. Manufacturing Expense
3.9. Regulatory Compliance
3.10. Competitive Landscape, 2022
3.10.1. Player Positioning Analysis
3.10.2. Key Strategies Adopted By Leading Players
CHAPTER 4. Manufacturing Plant Analysis
4.1. Manufacturing Plant Location and Establish Date of Major Manufacturers in 2022
4.2. R&D Status of Major Manufacturers in 2022
CHAPTER 5. Hemoglobinopathy Market By Type
5.1. Introduction
5.2. Hemoglobinopathy Revenue By Type
5.2.1. Hemoglobinopathy Revenue (USD Billion) and Forecast, By Type, 2020-2032
5.2.2. Thalassemia
5.2.2.1. Thalassemia Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
5.2.3. Sickle Cell Disease
5.2.3.1. Sickle Cell Disease Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
5.2.4. Others
5.2.4.1. Others Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
CHAPTER 6. Hemoglobinopathy Market By Therapy
6.1. Introduction
6.2. Hemoglobinopathy Revenue By Therapy
6.2.1. Hemoglobinopathy Revenue (USD Billion) and Forecast, By Therapy, 2020-2032
6.2.2. Monoclonal Antibody Medication
6.2.2.1. Monoclonal Antibody Medication Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
6.2.3. ACE inhibitors
6.2.3.1. ACE inhibitors Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
6.2.4. Hydroxyurea
6.2.4.1. Hydroxyurea Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
6.2.5. Others
6.2.5.1. Others Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
CHAPTER 7. Hemoglobinopathy Market By Distribution Channel
7.1. Introduction
7.2. Hemoglobinopathy Revenue By Distribution Channel
7.2.1. Hemoglobinopathy Revenue (USD Billion) and Forecast, By Distribution Channel, 2020-2032
7.2.2. Hospital Pharmacy
7.2.2.1. Hospital Pharmacy Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
7.2.3. Online Providers
7.2.3.1. Online Providers Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
7.2.4. Drug Stores and Retail Pharmacy
7.2.4.1. Drug Stores and Retail Pharmacy Market Revenue (USD Billion) and Growth Rate (%), 2020-2032
CHAPTER 8. North America Hemoglobinopathy Market By Country
8.1. North America Hemoglobinopathy Market Overview
8.2. U.S.
8.2.1. U.S. Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
8.2.2. U.S. Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
8.2.3. U.S. Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
8.3. Canada
8.3.1. Canada Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
8.3.2. Canada Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
8.3.3. Canada Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
8.4. North America PEST Analysis
CHAPTER 9. Europe Hemoglobinopathy Market By Country
9.1. Europe Hemoglobinopathy Market Overview
9.2. U.K.
9.2.1. U.K. Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
9.2.2. U.K. Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
9.2.3. U.K. Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
9.3. Germany
9.3.1. Germany Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
9.3.2. Germany Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
9.3.3. Germany Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
9.4. France
9.4.1. France Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
9.4.2. France Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
9.4.3. France Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
9.5. Spain
9.5.1. Spain Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
9.5.2. Spain Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
9.5.3. Spain Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
9.6. Rest of Europe
9.6.1. Rest of Europe Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
9.6.2. Rest of Europe Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
9.6.3. Rest of Europe Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
9.7. Europe PEST Analysis
CHAPTER 10. Asia Pacific Hemoglobinopathy Market By Country
10.1. Asia Pacific Hemoglobinopathy Market Overview
10.2. China
10.2.1. China Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.2.2. China Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.2.3. China Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.3. Japan
10.3.1. Japan Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.3.2. Japan Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.3.3. Japan Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.4. India
10.4.1. India Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.4.2. India Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.4.3. India Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.5. Australia
10.5.1. Australia Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.5.2. Australia Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.5.3. Australia Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.6. South Korea
10.6.1. South Korea Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.6.2. South Korea Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.6.3. South Korea Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.7. Rest of Asia-Pacific
10.7.1. Rest of Asia-Pacific Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
10.7.2. Rest of Asia-Pacific Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
10.7.3. Rest of Asia-Pacific Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
10.8. Asia Pacific PEST Analysis
CHAPTER 11. Latin America Hemoglobinopathy Market By Country
11.1. Latin America Hemoglobinopathy Market Overview
11.2. Brazil
11.2.1. Brazil Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
11.2.2. Brazil Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
11.2.3. Brazil Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
11.3. Mexico
11.3.1. Mexico Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
11.3.2. Mexico Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
11.3.3. Mexico Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
11.4. Rest of Latin America
11.4.1. Rest of Latin America Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
11.4.2. Rest of Latin America Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
11.4.3. Rest of Latin America Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
11.5. Latin America PEST Analysis
CHAPTER 12. Middle East & Africa Hemoglobinopathy Market By Country
12.1. Middle East & Africa Hemoglobinopathy Market Overview
12.2. GCC
12.2.1. GCC Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
12.2.2. GCC Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
12.2.3. GCC Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
12.3. South Africa
12.3.1. South Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
12.3.2. South Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
12.3.3. South Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
12.4. Rest of Middle East & Africa
12.4.1. Rest of Middle East & Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Type, 2020-2032
12.4.2. Rest of Middle East & Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Therapy, 2020-2032
12.4.3. Rest of Middle East & Africa Hemoglobinopathy Revenue (USD Billion) and Forecast By Distribution Channel, 2020-2032
12.5. Middle East & Africa PEST Analysis
CHAPTER 13. Player Analysis Of Hemoglobinopathy Market
13.1. Hemoglobinopathy Market Company Share Analysis
13.2. Competition Matrix
13.2.1. Competitive Benchmarking of key players by price, presence, market share, and R&D investment
13.2.2. New Product Launches and Product Enhancements
13.2.3. Mergers And Acquisition In Global Hemoglobinopathy Market
13.2.4. Partnership, Joint Ventures and Strategic Alliances/ Sales Agreements
CHAPTER 14. Company Profile
14.1. Pfizer, Inc.
14.1.1. Company Snapshot
14.1.2. Business Overview
14.1.3. Financial Overview
14.1.3.1. Revenue (USD Billion), 2022
14.1.3.2. Pfizer, Inc. 2022 Hemoglobinopathy Business Regional Distribution
14.1.4. Product /Service and Specification
14.1.5. Recent Developments & Business Strategy
14.2. Bio-Rad Laboratories Inc.
14.3. Siemens Healthineers
14.4. Danaher Corporation
14.5. Abbott Diagnostics
14.6. PerkinElmer Inc.
14.7. Nihon Kohden Corporation
14.8. Sysmex Corporation
14.9. Mindray Medical International Ltd.
14.10. Nexcelom Bioscience LLC.
14.11. Sangamo Therapeutics, Inc.
14.12. bluebird bio, Inc.