The Global Central Venous Catheters (CVCs) Market Size accounted for USD 832 Million in 2022 and is projected to achieve a market size of USD 1,367 Million by 2032 growing at a CAGR of 5.2% from 2023 to 2032.
Central Venous Catheters Market Highlights
- Global central venous catheters market revenue is expected to increase by USD 1,367 Million by 2032, with a 5.2% CAGR from 2023 to 2032
- North America region led with more than 49% of central venous catheters market share in 2022
- Asia-Pacific central venous catheters market growth will record a CAGR of around 6% from 2023 to 2032
- According to a 2015 study published in the journal Critical Care Medicine, central venous catheters are used by approximately 5 million patients per year in the United States
- By properties, the antimicrobial-coated segment of the CVC market is expected to grow at a CAGR of 5.6% during the forecast period
- Growing demand for sustainable agriculture practices, drives the central venous catheters market value
Central venous catheters (CVCs) are medical devices that are inserted into a patient's large vein, usually in the neck, chest, or groin, to administer medication, fluids, and nutrients, and to measure central venous pressure. They are also used for blood sampling and hemodialysis in critically ill patients. CVCs have become an essential tool in modern medicine, particularly in intensive care units (ICUs), where they are used to manage patients with complex medical conditions.
The global central venous catheters market has been experiencing steady growth in recent years, owing to the increasing incidence of chronic diseases, such as cancer and kidney failure, and the growing number of surgeries and medical procedures that require CVCs. Factors driving the growth of the CVC market include technological advancements in catheter design and materials, an increasing number of hospitals and healthcare facilities, and the rising geriatric population. However, the market is also facing some challenges, such as the risk of infection and complications associated with CVCs, which has led to the development of new and improved catheter materials and insertion techniques to reduce these risks. Additionally, the high cost of CVCs and the availability of alternative medical devices are also potential barriers to market growth.
Global Central Venous Catheters Market Trends
Market Drivers
- Increasing prevalence of chronic diseases
- Growing number of surgeries and medical procedures
- Advancements in catheter design and materials
- Rising geriatric population
- Increase in hospital and healthcare facilities
Market Restraints
- Risk of infection and complications associated with CVCs
- High cost of CVCs
Market Opportunities
- Growing demand for minimally invasive procedures
- Development of antimicrobial and antithrombogenic catheter coatings
Central Venous Catheters Market Report Coverage
Market |
Central Venous Catheters Market |
Central Venous Catheters Market Size 2022 |
USD 832 Million |
Central Venous Catheters Market Forecast 2032 |
USD 1,367 Million |
Central Venous Catheters Market CAGR During 2023 - 2032 |
5.2% |
Central Venous Catheters Market Analysis Period |
2020 - 2032 |
Central Venous Catheters Market Base Year |
2022 |
Central Venous Catheters Market Forecast Data |
2023 - 2032 |
Segments Covered |
By Design, By Property, By Application, By End User, And By Geography
|
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and Middle East & Africa |
Key Companies Profiled |
Becton, Dickinson and Company, Teleflex Incorporated, C. R. Bard, Inc., Cook Medical Inc., Edwards Lifesciences Corporation, AngioDynamics, Inc., Smiths Medical, Inc., B. Braun Melsungen AG, Vygon SA, Argon Medical Devices, Inc., Terumo Corporation, and Medtronic plc.
|
Report Coverage
|
Market Trends, Drivers, Restraints, Competitive Analysis, Player Profiling, Covid-19 Analysis, Regulation Analysis |
Central Venous Catheters Market Dynamics
Arterial access catheters are used to provide fluids, drugs, and nutrients such as analgesics, antipyretics, and antibiotics when the patient is unable to consume food on their own. It is also used for the rectification of electrolyte unevenness and plasma transfusion in patients. These devices use an intravenous route of supervision that permits quick distribution of fluids and medication.
The market is driven by high dominance in the occurrence of chronic disorders, growing adoption, and a rising mandate for antimicrobial-coated catheters, along with increasing syndrome occurrences due to the rising senior population. In addition, increasing rates of hospitalizations and product innovations are also driving the growth of this market. The major challenge hampering the growth of the market is mechanical complications and lack of knowledge among the population for adoption. The rising popularity of antimicrobial CVCs and the increase in the number of oncologists recommending disinfectant-coated tunneled catheters for chemotherapy treatments further pave opportunities for the growth of this market. In addition, an upsurge in the usage of tip location devices is enormously expected to grow this market in future years.
Central Venous Catheters Market Segmentation
The global central venous catheters market segmentation is based on design, property, application, end user, and geography.
Central Venous Catheters Market By Design
- Multi-Lumen
- Single-Lumen
- Double-Lumen
- Triple-Lumen
According to the central venous catheters industry analysis, the multi-lumen segment accounted for the largest market share in 2022. Multi-lumen central venous catheters (CVCs) are medical devices that have multiple channels or lumens within a single catheter, which allow for the administration of multiple medications or fluids simultaneously. These devices are commonly used in critical care settings, where patients require multiple therapies, such as hemodialysis, parenteral nutrition, and antibiotic therapy. The multi-lumen segment of the CVC market has been experiencing significant growth in recent years, owing to its ability to improve patient outcomes and reduce the need for additional catheter insertions. The increasing prevalence of chronic diseases and the growing demand for minimally invasive procedures are some of the key factors driving the growth of the multi-lumen segment.
Central Venous Catheters Market By Property
- Antimicrobial Coated
- Non-antimicrobial Coated
In terms of properties, the antimicrobial coated segment is expected to witness significant growth in the coming years. Antimicrobial coated central venous catheters (CVCs) are medical devices that are coated with substances that prevent or inhibit the growth of microorganisms, such as bacteria, fungi, and viruses. These coatings can be applied to the surface of the catheter, or they can be impregnated into the catheter material itself. The antimicrobial coated segment of the CVC market has been experiencing significant growth in recent years, owing to their ability to reduce the risk of catheter-related infections, which are a major cause of morbidity and mortality in hospitalized patients. The increasing prevalence of catheter-related infections, the growing demand for minimally invasive procedures, and the development of advanced coating technologies are some of the key factors driving the growth of the antimicrobial coated segment.
Central Venous Catheters Market By Application
- Jugular Vein
- Subclavian Vein
- Femoral Vein
According to the central venous catheters market forecast, the jugular vein segment is expected to witness significant growth in the coming years. Jugular vein central venous catheters (CVCs) are medical devices that are inserted through the jugular vein in the neck and advanced into the superior vena cava or right atrium of the heart. These catheters are commonly used in critical care settings, where patients require frequent and prolonged access to the central venous system. The jugular vein segment of the CVC market has been experiencing significant growth in recent years, owing to their ability to provide rapid and reliable access to the central venous system, as well as their lower risk of pneumothorax compared to other insertion sites.
Central Venous Catheters Market By End User
- Hospitals
- Ambulatory Surgical Centers
- Others
Based on the end user, the hospitals segment is the largest end-user segment of the central venous catheters (CVC) market, as these devices are commonly used in critical care settings, such as intensive care units (ICUs), emergency departments, and surgical suites, where patients require frequent and prolonged access to the central venous system. The hospitals segment includes both public and private hospitals, as well as academic medical centers, which provide advanced care and research facilities. The hospitals segment of the CVC market has been experiencing significant growth in recent years, owing to the increasing prevalence of chronic diseases, the growing demand for minimally invasive procedures, and the need for effective infection control measures.
Central Venous Catheters Market Regional Outlook
North America
Europe
- U.K.
- Germany
- France
- Spain
- Rest of Europe
Asia-Pacific
- India
- Japan
- China
- Australia
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Mexico
- Rest of Latin America
The Middle East & Africa
- South Africa
- GCC Countries
- Rest of the Middle East & Africa (ME&A)
Central Venous Catheters Market Regional Analysis
North America dominates the central venous catheters (CVC) market, accounting for the largest share of the global market. This can be attributed to several factors, including the presence of a well-established healthcare infrastructure, a high incidence of chronic diseases, and the availability of advanced medical technologies. The region is also home to several leading players in the CVC market, which have a strong presence and a wide range of product offerings. The high healthcare expenditure and favorable reimbursement policies in the region also contribute to the growth of the CVC market in North America. The US is the largest market for CVCs in North America, owing to the presence of a large patient pool, a well-established healthcare infrastructure, and the increasing adoption of advanced medical technologies. The region is also witnessing significant investments in research and development activities for the development of new and innovative CVCs, which is expected to drive the growth of the market in the coming years.
Central Venous Catheters Market Player
Some of the top central venous catheters market companies offered in the professional report include Becton, Dickinson and Company, Teleflex Incorporated, C. R. Bard, Inc., Cook Medical Inc., Edwards Lifesciences Corporation, AngioDynamics, Inc., Smiths Medical, Inc., B. Braun Melsungen AG, Vygon SA, Argon Medical Devices, Inc., Terumo Corporation, and Medtronic plc.
CHAPTER 1. Industry Overview of Central Venous Catheters Market
1.1. Definition and Scope
1.1.1. Definition of Central Venous Catheters
1.1.2. Market Segmentation
1.1.3. Years Considered for the Study
1.1.4. Assumptions and Acronyms Used
1.1.4.1. Market Assumptions and Market Forecast
1.1.4.2. Acronyms Used in Global Central Venous Catheters Market
1.2. Summary
1.2.1. Executive Summary
1.2.2. Central Venous Catheters Market By Design
1.2.3. Central Venous Catheters Market By Property
1.2.4. Central Venous Catheters Market By Application
1.2.5. Central Venous Catheters Market By End User
1.2.6. Central Venous Catheters Market By Region
CHAPTER 2. Research Approach
2.1. Methodology
2.1.1. Research Programs
2.1.2. Market Size Estimation
2.1.3. Market Breakdown and Data Triangulation
2.2. Data Source
2.2.1. Secondary Source
2.2.2. Primary Source
CHAPTER 3. Market Dynamics And Competition Analysis
3.1. Market Drivers
3.1.1. Driver 1
3.1.2. Driver 2
3.2. Restraints and Challenges
3.2.1. Restraint 1
3.2.2. Restraint 2
3.3. Growth Opportunities
3.3.1. Opportunity 1
3.3.2. Opportunity 2
3.4. Porter’s Five Forces Analysis
3.4.1. Bargaining Power of Suppliers
3.4.2. Bargaining Power of Buyers
3.4.3. Threat of Substitute
3.4.4. Threat of New Entrants
3.4.5. Degree of Competition
3.5. Market Concentration Ratio and Market Maturity Analysis of Central Venous Catheters Market
3.5.1. Go To Market Strategy
3.5.1.1. Introduction
3.5.1.2. Growth
3.5.1.3. Maturity
3.5.1.4. Saturation
3.5.1.5. Possible Development
3.6. Technological Roadmap for Central Venous Catheters Market
3.7. Value Chain Analysis
3.7.1. List of Key Manufacturers
3.7.2. List of Customers
3.7.3. Level of Integration
3.8. Price Trend of Key Raw Material
3.8.1. Raw Material Suppliers
3.8.2. Proportion of Manufacturing Cost Structure
3.8.2.1. Raw Material
3.8.2.2. Labor Cost
3.8.2.3. Manufacturing Expense
3.9. Regulatory Compliance
3.10. Competitive Landscape, 2022
3.10.1. Player Positioning Analysis
3.10.2. Key Strategies Adopted By Leading Players
CHAPTER 4. Manufacturing Plant Analysis
4.1. Manufacturing Plant Location and Establish Date of Major Manufacturers in 2022
4.2. R&D Status of Major Manufacturers in 2022
CHAPTER 5. Central Venous Catheters Market By Design
5.1. Introduction
5.2. Central Venous Catheters Revenue By Design
5.2.1. Central Venous Catheters Revenue (USD Million) and Forecast, By Design, 2020-2032
5.2.2. Multi-Lumen
5.2.2.1. Multi-Lumen Market Revenue (USD Million) and Growth Rate (%), 2020-2032
5.2.3. Single-Lumen
5.2.3.1. Single-Lumen Market Revenue (USD Million) and Growth Rate (%), 2020-2032
5.2.4. Double-Lumen
5.2.4.1. Double-Lumen Market Revenue (USD Million) and Growth Rate (%), 2020-2032
5.2.5. Triple-Lumen
5.2.5.1. Triple-Lumen Market Revenue (USD Million) and Growth Rate (%), 2020-2032
CHAPTER 6. Central Venous Catheters Market By Property
6.1. Introduction
6.2. Central Venous Catheters Revenue By Property
6.2.1. Central Venous Catheters Revenue (USD Million) and Forecast, By Property, 2020-2032
6.2.2. Antimicrobial Coated
6.2.2.1. Antimicrobial Coated Market Revenue (USD Million) and Growth Rate (%), 2020-2032
6.2.3. Non-antimicrobial Coated
6.2.3.1. Non-antimicrobial Coated Market Revenue (USD Million) and Growth Rate (%), 2020-2032
CHAPTER 7. Central Venous Catheters Market By Application
7.1. Introduction
7.2. Central Venous Catheters Revenue By Application
7.2.1. Central Venous Catheters Revenue (USD Million) and Forecast, By Application, 2020-2032
7.2.2. Jugular Vein
7.2.2.1. Jugular Vein Market Revenue (USD Million) and Growth Rate (%), 2020-2032
7.2.3. Subclavian Vein
7.2.3.1. Subclavian Vein Market Revenue (USD Million) and Growth Rate (%), 2020-2032
7.2.4. Femoral Vein
7.2.4.1. Femoral Vein Market Revenue (USD Million) and Growth Rate (%), 2020-2032
CHAPTER 8. Central Venous Catheters Market By End User
8.1. Introduction
8.2. Central Venous Catheters Revenue By End User
8.2.1. Central Venous Catheters Revenue (USD Million) and Forecast, By End User, 2020-2032
8.2.2. Hospitals
8.2.2.1. Hospitals Market Revenue (USD Million) and Growth Rate (%), 2020-2032
8.2.3. Ambulatory Surgical Centers
8.2.3.1. Ambulatory Surgical Centers Market Revenue (USD Million) and Growth Rate (%), 2020-2032
8.2.4. Others
8.2.4.1. Others Market Revenue (USD Million) and Growth Rate (%), 2020-2032
CHAPTER 9. North America Central Venous Catheters Market By Country
9.1. North America Central Venous Catheters Market Overview
9.2. U.S.
9.2.1. U.S. Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
9.2.2. U.S. Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
9.2.3. U.S. Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
9.2.4. U.S. Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
9.3. Canada
9.3.1. Canada Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
9.3.2. Canada Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
9.3.3. Canada Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
9.3.4. Canada Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
9.4. North America PEST Analysis
CHAPTER 10. Europe Central Venous Catheters Market By Country
10.1. Europe Central Venous Catheters Market Overview
10.2. U.K.
10.2.1. U.K. Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
10.2.2. U.K. Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
10.2.3. U.K. Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
10.2.4. U.K. Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
10.3. Germany
10.3.1. Germany Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
10.3.2. Germany Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
10.3.3. Germany Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
10.3.4. Germany Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
10.4. France
10.4.1. France Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
10.4.2. France Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
10.4.3. France Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
10.4.4. France Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
10.5. Spain
10.5.1. Spain Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
10.5.2. Spain Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
10.5.3. Spain Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
10.5.4. Spain Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
10.6. Rest of Europe
10.6.1. Rest of Europe Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
10.6.2. Rest of Europe Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
10.6.3. Rest of Europe Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
10.6.4. Rest of Europe Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
10.7. Europe PEST Analysis
CHAPTER 11. Asia Pacific Central Venous Catheters Market By Country
11.1. Asia Pacific Central Venous Catheters Market Overview
11.2. China
11.2.1. China Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.2.2. China Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.2.3. China Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.2.4. China Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.3. Japan
11.3.1. Japan Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.3.2. Japan Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.3.3. Japan Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.3.4. Japan Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.4. India
11.4.1. India Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.4.2. India Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.4.3. India Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.4.4. India Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.5. Australia
11.5.1. Australia Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.5.2. Australia Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.5.3. Australia Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.5.4. Australia Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.6. South Korea
11.6.1. South Korea Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.6.2. South Korea Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.6.3. South Korea Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.6.4. South Korea Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.7. Rest of Asia-Pacific
11.7.1. Rest of Asia-Pacific Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
11.7.2. Rest of Asia-Pacific Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
11.7.3. Rest of Asia-Pacific Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
11.7.4. Rest of Asia-Pacific Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
11.8. Asia Pacific PEST Analysis
CHAPTER 12. Latin America Central Venous Catheters Market By Country
12.1. Latin America Central Venous Catheters Market Overview
12.2. Brazil
12.2.1. Brazil Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
12.2.2. Brazil Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
12.2.3. Brazil Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
12.2.4. Brazil Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
12.3. Mexico
12.3.1. Mexico Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
12.3.2. Mexico Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
12.3.3. Mexico Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
12.3.4. Mexico Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
12.4. Rest of Latin America
12.4.1. Rest of Latin America Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
12.4.2. Rest of Latin America Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
12.4.3. Rest of Latin America Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
12.4.4. Rest of Latin America Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
12.5. Latin America PEST Analysis
CHAPTER 13. Middle East & Africa Central Venous Catheters Market By Country
13.1. Middle East & Africa Central Venous Catheters Market Overview
13.2. GCC
13.2.1. GCC Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
13.2.2. GCC Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
13.2.3. GCC Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
13.2.4. GCC Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
13.3. South Africa
13.3.1. South Africa Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
13.3.2. South Africa Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
13.3.3. South Africa Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
13.3.4. South Africa Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
13.4. Rest of Middle East & Africa
13.4.1. Rest of Middle East & Africa Central Venous Catheters Revenue (USD Million) and Forecast By Design, 2020-2032
13.4.2. Rest of Middle East & Africa Central Venous Catheters Revenue (USD Million) and Forecast By Property, 2020-2032
13.4.3. Rest of Middle East & Africa Central Venous Catheters Revenue (USD Million) and Forecast By Application, 2020-2032
13.4.4. Rest of Middle East & Africa Central Venous Catheters Revenue (USD Million) and Forecast By End User, 2020-2032
13.5. Middle East & Africa PEST Analysis
CHAPTER 14. Player Analysis Of Central Venous Catheters Market
14.1. Central Venous Catheters Market Company Share Analysis
14.2. Competition Matrix
14.2.1. Competitive Benchmarking Of Key Players By Price, Presence, Market Share, And R&D Investment
14.2.2. New Design Launches and Design Enhancements
14.2.3. Mergers And Acquisition In Global Central Venous Catheters Market
14.2.4. Partnership, Joint Ventures and Strategic Alliances/ Sales Agreements
CHAPTER 15. Company Profile
15.1. Becton, Dickinson and Company
15.1.1. Company Snapshot
15.1.2. Business Overview
15.1.3. Financial Overview
15.1.3.1. Revenue (USD Million), 2022
15.1.3.2. Becton, Dickinson and Company 2022 Central Venous Catheters Business Regional Distribution
15.1.4. Design /Service and Specification
15.1.5. Recent Developments & Business Strategy
15.2. Teleflex Incorporated
15.3. C. R. Bard, Inc.
15.4. Cook Medical Inc.
15.5. Edwards Lifesciences Corporation
15.6. AngioDynamics, Inc.
15.7. Smiths Medical, Inc.
15.8. B. Braun Melsungen AG
15.9. Vygon SA
15.10. Argon Medical Devices, Inc.
15.11. Terumo Corporation
15.12. Medtronic plc.