The global basal cell carcinoma treatment market is expected to grow at a CAGR of around 9.2% from 2020 to 2027 and expected to reach the market value of around US$ 11.5 Bn by 2027.
Basal cell carcinoma is the most common form of cancer in humans. It is a type of non-melanoma skin cancer that starts in the basal cell layer of the epidermis (the top layer of skin), grows slowly, and rarely spreads (metastasizes). The primary cause of basal cell carcinoma is overexposure to the sun and those with fair complexions are especially susceptible. Basal cell carcinoma is often easily detected and has a proven track record for successful treatment. Early diagnosis and treatment can prevent damage to the areas around cancer and decrease the risk associated with recurrence and metastasis. According to the American Cancer Society, Inc., about 5.4 million basal squamous cell skin cancers are diagnosed every year in the US (occurring in about 3.3 million Americans, as some people have more than one). About 8 out of 10 of these are basal cell cancers.
Surging demand for targeted drugs contribute for the growth of basal cell carcinoma market
Targeted drugs called "hedgehog pathway inhibitors" assist patients suffering from basal cell nevus syndrome. For instance, the drug “Vismodegib (Erivedge)” has shown proven records by lowering the number of new basal cell cancers and shrink existing tumors in people suffering from the syndrome. As per the American Cancer Society, Inc., the two common targeted therapies for basal cell carcinoma involve "Hedgehog pathway inhibitors" and "EGFR inhibitors". Under EGFR inhibitors, “Vismodegib (Erivedge)” and “Sonidegib (Odomzo)” are used as targeted drugs that can be used to treat some advanced or recurrent basal cell skin cancers. Furthermore, under EGFR inhibitors, targeted drug involve "cetuximab (Erbitux)" has shown promising results for the treatment of basal cell carcinoma.
Big calls for "Immunotherapy" in basal cell carcinoma
With the advancements in targeted therapies, immunotherapy has grabbed significant attention in the global basal cell carcinoma market. Activating or modulating the immune system to treat basal cell carcinoma has shown better and sustained outcomes. Three immune modulator drugs are approved by the Food and Drug Administration (FDA). These involve “imiquimod”, “Sonidegib”, “Vismodegib”, and several other are under investigation in clinical trials. The role of combination therapy is also emerging and will gain a significant pace in the forecast period. It is assumed that immunotherapy will soon transform the standards of care for basal cell carcinoma. Additionally, Cancer Research Institute has approved six other immune modulators are approved by the FDA as a treatment option for immunotherapy. These include “Aldesleukin Proleukin®”, “Atezolizumab Tecentriq®”, “Avelumab Bavencio®”, “Cemiplimab Libtayo®”, “Ipilimumab Yervoy®”, “Nivolumab Opdivo®”, “Peginterferon alfa-2b Sylatron®/PEG-Intron®”, “Pembrolizumab Keytruda®”, and “Poly ICLC Hiltonol®”.
Key takeaways
In February 2021, the US Food and Drug Administration (USFDA), approved intravenous immunotherapy medication, “cemiplimab-rwlc Libtayo®” for treatment of patients suffering from advanced basal cell carcinoma (BCC). This is considered as an advanced immunotherapy medication over hedgehog pathway inhibitor (HHI) or for whom an HHI is not appropriate. Full approval was granted to patients with locally advanced BCC and accelerated approval was granted to patients with metastatic BCC.
Segmental Analysis
Basal cell carcinoma market is segmented on the basis of treatment type and end-user. Based on treatment type, the market is split into surgery, medication, and others. Surgery is further segmented as Mohs Surgery, Excisional Surgery, Cryosurgery, and Laser Surgery. Further, on the basis of end-user, the market is segmented as hospitals, specialty clinics, and among others.
Surgery to take a front lead in driving the basal cell carcinoma (BCC) market globally
Different surgeries involved for the treatment of basal cell carcinoma involve Mohs Surgery, Excisional Surgery, Cryosurgery, And Laser Surgery. Among the surgeries, Mohs surgery is the most effective and gold standard technique for removing BCCs that harms minimal healthy tissue with the highest possible cure rate up to 99% on tumors treated for the first time. The technique is often recommended by physicians for patients having BCCs located in areas around the nose, eyes, lips, scalp, fingers, toes, or genitals. Additionally, for small and early BCCs that have not spread, Excisional surgery is a frequent treatment recommended by physicians. Cure rates are above 95%. Also, cryosurgery plays a vital role for effective, superficial BCCs. The cure rate is between 85% and 90%. This technique is used less commonly for invasive BCC due to its associated recurrence harder to detect. Furthermore, laser surgery is not yet approved by the FDA for superficial BCCs but is sometimes used as a secondary therapy, especially when other techniques have unsuccessful results.
Regional Landscape
North America dominates the basal cell carcinoma market and will continue the same trend in the forthcoming years
North America has a dominating share for the overall basal cell carcinoma market followed by Europe. The factors responsible for the regional growth involves rising awareness of the advanced treatments, favorable reimbursement policies, and high prevalence of basal cell carcinoma in this region resulting in higher demand for treatment options. As per the estimates revealed by the American Academy of Dermatology Association, basal cell carcinoma affects more than 3 million Americans every year. Research indicates that the overall incidence of BCC increased by 145% between 1976-1984 and 2000-2010, and the overall incidence increased to 263% over the same period. The basal cell carcinoma can be prevented. The best way to lower it can be achieved by educating people about the skin cancer risk factors, prevention, and detection. Furthermore, the American Academy of Dermatology (AAD) sponsors annual free skin cancer screenings throughout the country. On the other hand, Asia Pacific is expected to witness a record remarkable growth rate in the coming years owing to high government involvement, funding assistance for the research activities, and availability of new treatment options. Such factors are responsible for the growth of the basal cell carcinoma treatment market in Asia Pacific region.
Competitive Landscape
The global basal cell carcinoma market is led by the prominent players that involve Sun Pharmaceutical Industries Ltd., Bausch Health Companies Inc., Mylan N.V., Merck & Co., Inc., F. Hoffmann-La Roche Ltd., Allergan, Perrigo Company plc, Strides Pharma Science Limited., and among others.
Market Segmentation
Market By Treatment Type
Surgery
- Mohs Surgery
- Excisional Surgery
- Cryosurgery
- Laser Surgery
Medication
Others
Market By End User
Hospitals
Specialty Clinics
Others
Market By Geography
North America
Europe
- U.K.
- Germany
- France
- Spain
- Rest of Europe
Asia-Pacific
- China
- Japan
- India
- Australia
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Mexico
- Rest of Latin America
Middle East & Africa
- GCC
- South Africa
- Rest of Middle East & Africa
CHAPTER 1. Industry Overview of Basal Cell Carcinoma Treatment
1.1. Definition and Scope
1.1.1. Definition of Basal Cell Carcinoma Treatment
1.1.2. Market Segmentation
1.1.3. Years Considered for the Study
1.1.4. Assumptions and Acronyms Used
1.1.4.1. Market Assumptions and Market Forecast
1.1.4.2. Acronyms Used in Global Basal Cell Carcinoma Treatment Market
1.2. Summary
1.2.1. Executive Summary
1.2.2. Basal Cell Carcinoma Treatment Market By Treatment Type
1.2.3. Basal Cell Carcinoma Treatment Market By End User
1.2.4. Basal Cell Carcinoma Treatment Market by Regions
CHAPTER 2. Research Approach
2.1. Methodology
2.1.1. Research Programs
2.1.2. Market Size Estimation
2.1.3. Market Breakdown and Data Triangulation
2.2. Data Source
2.2.1. Secondary Sources
2.2.2. Primary Sources
CHAPTER 3. Market Dynamics And Competition Analysis
3.1. Market Drivers
3.1.1. Driver 1
3.1.2. Driver 2
3.2. Restraints and Challenges
3.2.1. Restrain 1
3.2.2. Restrain 2
3.3. Growth Opportunities
3.3.1. Opportunity 1
3.3.2. Opportunity 2
3.4. Porter’s Five Forces Analysis
3.4.1. Bargaining Power of Suppliers
3.4.2. Bargaining Power of Buyers
3.4.3. Threat of Substitute
3.4.4. Threat of New Entrants
3.4.5. Degree of Competition
3.5. Market Concentration Ratio and Market Maturity Analysis of Basal Cell Carcinoma Treatment Market
3.5.1. Go To Market Strategy
3.5.1.1. Introduction
3.5.1.2. Growth
3.5.1.3. Maturity
3.5.1.4. Saturation
3.5.1.5. Possible Development
3.6. Technological Roadmap for Basal Cell Carcinoma Treatment Market
3.7. Value Chain Analysis
3.7.1. List of Key Manufacturers
3.7.2. List of Customers
3.7.3. Level of Integration
3.8. Cost Structure Analysis
3.8.1. Price Trend of Key Raw Materials
3.8.2. Raw Material Suppliers
3.8.3. Proportion of Manufacturing Cost Structure
3.8.3.1. Raw Material
3.8.3.2. Labor Cost
3.8.3.3. Manufacturing Expense
3.9. Regulatory Compliance
3.10. Competitive Landscape, 2019
3.10.1. Player Positioning Analysis
3.10.2. Key Strategies Adopted By Leading Players
CHAPTER 4. Manufacturing Plant Analysis
4.1. Manufacturing Plant Location and Establish Date of Major Manufacturers in 2019
4.2. R&D Status and Application Source of Basal Cell Carcinoma Treatment Major Manufacturers in 2019
CHAPTER 5. Basal Cell Carcinoma Treatment Market By Treatment Type
5.1. Introduction
5.2. Basal Cell Carcinoma Treatment Revenue By Treatment Type
5.2.1. Basal Cell Carcinoma Treatment Revenue (US$ Mn) and Forecast, By Treatment Type, 2016-2027
5.2.2. Surgery
5.2.2.1. Surgery Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.2.2. Mohs Surgery
5.2.2.2.1. Mohs Surgery Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.2.3. Excisional Surgery
5.2.2.3.1. Excisional Surgery Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.2.4. Cryosurgery Surgery
5.2.2.4.1. Cryosurgery Surgery Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.2.5. Laser Surgery
5.2.2.5.1. Laser Surgery Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.3. Medication
5.2.3.1. Medication Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
5.2.4. Others
5.2.4.1. Others Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
CHAPTER 6. Basal Cell Carcinoma Treatment Market Revenue By End User
6.1. Introduction
6.2. Basal Cell Carcinoma Treatment Revenue (US$ Mn) By End User
6.2.1. Basal Cell Carcinoma Treatment Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
6.2.2. Hospitals
6.2.2.1. Hospitals Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
6.2.3. Specialty Clinics
6.2.3.1. Specialty Clinics Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
6.2.4. Others
6.2.4.1. Others Market Revenue (US$ Mn) and Growth Rate (%), 2016-2027
CHAPTER 7. North America Basal Cell Carcinoma Treatment Market By Country
7.1. North America Basal Cell Carcinoma Treatment Overview
7.2. U.S.
7.2.1. U.S. Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
7.2.2. U.S. Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
7.3. Canada
7.3.1. Canada Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
7.3.2. Canada Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
7.4. North America PEST Analysis
CHAPTER 8. Europe Basal Cell Carcinoma Treatment Market By Country
8.1. Europe Basal Cell Carcinoma Treatment Market Overview
8.2. U.K.
8.2.1. U.K. Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
8.2.2. U.K. Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
8.3. Germany
8.3.1. Germany Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
8.3.2. Germany Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
8.4. France
8.4.1. France Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
8.4.2. France Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
8.5. Spain
8.5.1. Spain Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
8.5.2. Spain Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
8.6. Rest of Europe
8.6.1. Rest of Europe Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016-2027
8.6.2. Rest of Europe Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016-2027
8.7. Europe PEST Analysis
CHAPTER 9. Asia Pacific Basal Cell Carcinoma Treatment Market By Country
9.1. Asia Pacific Basal Cell Carcinoma Treatment Market Overview
9.2. China
9.2.1. China Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.2.2. China Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.3. Japan
9.3.1. Japan Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.3.2. Japan Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.4. India
9.4.1. India Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.4.2. India Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.5. Australia
9.5.1. Australia Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.5.2. Australia Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.6. South Korea
9.6.1. South Korea Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.6.2. South Korea Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.7. Rest of Asia-Pacific
9.7.1. Rest of Asia-Pacific Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
9.7.2. Rest of Asia-Pacific Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
9.8. Asia Pacific PEST Analysis
CHAPTER 10. Latin America Basal Cell Carcinoma Treatment Market By Country
10.1. Latin America Basal Cell Carcinoma Treatment Market Overview
10.2. Brazil
10.2.1. Brazil Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
10.2.2. Brazil Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
10.3. Mexico
10.3.1. Mexico Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
10.3.2. Mexico Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
10.4. Rest of Latin America
10.4.1. Rest of Latin America Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 – 2027
10.4.2. Rest of Latin America Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
CHAPTER 11. Middle East & Africa Basal Cell Carcinoma Treatment Market By Country
11.1. Middle East & Africa Basal Cell Carcinoma Treatment Market Overview
11.2. Saudi Arabia
11.2.1. Saudi Arabia Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
11.2.2. Saudi Arabia Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
11.3. UAE
11.3.1. UAE Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
11.3.2. UAE Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
11.4. Rest of Middle East & Africa
11.4.1. Rest of Middle East & Africa Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By Treatment Type, 2016 - 2027
11.4.2. Rest of Middle East & Africa Basal Cell Carcinoma Treatment Market Revenue (US$ Mn) and Forecast By End User, 2016 - 2027
CHAPTER 12. Player Analysis Of Basal Cell Carcinoma Treatment
12.1. Basal Cell Carcinoma Treatment Market Company Share Analysis
12.2. Competition Matrix
12.2.1. Competitive Benchmarking of key players by price, presence, market share, and R&D investment
12.2.2. New Product Launches and Product Enhancements
12.2.3. Mergers And Acquisition In Global Basal Cell Carcinoma Treatment Market
12.2.4. Partnership, Joint Ventures and Strategic Alliances/ Sales Agreements
CHAPTER 13. COMPANY PROFILE
13.1. Sun Pharmaceutical Industries Ltd.
13.1.1. Company Snapshot
13.1.2. Business Overview
13.1.3. Financial Overview
13.1.3.1. Revenue (US$ Mn), 2019
13.1.3.2. Sun Pharmaceutical Industries Ltd. 2019 Basal Cell Carcinoma Treatment Business Regional Distribution
13.1.4. Product/ Service and Specification
13.1.5. Recent Developments & Business Strategy
13.1.6. Manufacturing Plant Footprint Analysis
13.2. Bausch Health Companies Inc.
13.3. Mylan N.V.
13.4. Merck & Co., Inc.
13.5. F. Hoffmann-La Roche Ltd.
13.6. Allergan
13.7. Perrigo Company plc
13.8. Strides Pharma Science Limited
13.9. Others