The Global Aptamers Market size accounted for USD 1,229 Million in 2021 and is expected to reach the value of USD 5,957 Million by 2030 at a CAGR of 19.6% during the forecast period from 2022 to 2030.

Aptamers market growth is being driven by an increase in the number of clinical trials to advance aptamer-based new therapies, as well as increased investment in pharmaceutical R&D. Additionally, advances in the systematic evolution of ligands by exponential enrichment (SELEX) procedure for retrieving high-quality aptamers are expected to drive the growth of the aptamers market size.

Aptamers are single-stranded DNA, RNA, or synthetic XNA particles with high sensitivity and specificity that can be designed to interact with any desired point. They have been widely used to accelerate basic research discoveries, ensure food quality and safety, and monitor environmental conditions. Aptamers have the potential to be used as clinical laboratories and therapeutic drugs. Aptamers are commonly truncated at the sugars to reduce synthesis costs, capped at their termini to increase nuclease resistance, and covalently linked to polyethylene glycol or the other entity to decrease renal filtration rates. Furthermore, despite the fact that binding to specific cell-surface targets can result in internalization, aptamers can be used to improve therapeutic cargoes like short interfering RNA.

Aptamers Market Dynamics

Drivers

• Rising use of aptamers in drug development and therapeutic techniques
• Growing awareness of the benefits of aptamers over antibodies
• Increasing incidence of the chronic and genetic disorder
• Increased R&D investments by the pharmaceutical and biotechnology industries

Restraints

• Stringent regulation in the use of aptamers
• Low market acceptance

Opportunity

• Increase in venture capital funding for aptamer investigation

Report Coverage

The rising prevalence of life-threatening diseases such as cardiovascular, neurodegenerative, cancer, and acquired immunodeficiency syndrome is one of the important factors that influence the demand for new and more effective detection assays based on aptamer diagnosis. In addition, the emergence of the electrochemical conversion process to increase nuclease resistance and the therapeutic potential of aptamers is driving the market growth. Aptamers market trend can also be attributed to a surge in the percentage of Research & development activities performed to enhance diagnostic drugs, devices, and carriers.

Apart from that, since aptamers are chemically synthesized, reducing batch-to-batch variability and needing less development time, their use is rapidly expanding around the world. Furthermore, many international corporations are collaborating and partnering with educational institutions and academic laboratories to launch next-generation products and strengthen their market presence. Aptamers are expected to become more widely used in a variety of clinical therapies, as well as in the food and beverage industries.

Aptamers Market Segmentation

The global aptamers market segmentation is based on type, application, end-user, and region.

Aptamers Market By Type

• Nucleic Acid Aptamers
  • DNA-Based Aptamers
  • RNA-Based Aptamers
  • XNA-Based Aptamers
• Peptide Aptamers

Based on the type, the market can be segmented into nucleic acid and peptide. Over the next few years, the nucleic acid segment is anticipated to dominate the market. The nucleic acid is even further subdivided into DNA-based, RNA-based, and XNA-based aptamers. In 2021, the segment of DNA-based aptamers will have the largest aptamers market share. The high market share of DNA aptamers is due to their lower operating costs and greater stability compared to certain other nucleic acid-based aptamers, as well as their growing prevalence over the globe.

Furthermore, owing to the excessive application base for diagnostic and therapeutic applications, the peptide aptamer segment is projected to experience profitable market growth in the near future.

Aptamers Market By Application

• Diagnostics
• Research And Development
• Therapeutics
• Others

In terms of application, the research and development segment is expected to lead the global aptamers industry in 2021. Rising demand for aptamers, as well as increased research projects in this field, are driving the segment's growth. Collaboration, partnerships, and contractual arrangements are among the corporate strategy initiatives undertaken by prominent stakeholders for the R&D activities of emerging aptamer-based diagnostics and treatment products that drive segment growth. Furthermore, the diagnostic segment is expected to grow at the fastest rate in the coming years due to the rising prevalence of chronic illnesses and the development of new clinical diagnostics to identify serious medical conditions. Appropriate treatment is the most important element in the treatment of various diseases, particularly viral diseases. Aptamer technology has grown in popularity and use in recent years all over the world. It has been used in a variety of cancer diagnoses and therapy, and several strategies using aptamers against virus proteins are currently being researched definitively or conclusively.

Aptamers Market By End-User

• Pharmaceutical & Biotechnology Companies
• Academic & Government Research Institutes
• CROs
• Others

According to the global aptamers market forecast, pharmaceutical and biotechnology companies dominated the market due to an increasing number of market participants offering custom aptamers for use in therapeutic agent advancement and rising R&D expenditure. Due to advancements in diagnostic equipment for cancer and other diseases, as well as the increasing prevalence of serious viral and infectious diseases, this segment will grow at the fastest rate during the forecast period. Furthermore, the increasing number of epidemiological studies evaluating aptamers for novel therapeutic, as well as an international collaboration between aptamer companies and well-known pharmaceutical and biopharmaceutical companies are driving growth.

Aptamers Market Regional Outlook

North America

• U.S.
• Canada

Europe

• U.K.
• Germany
• France
• Spain
• Rest of Europe

Latin America

• Mexico
• Brazil
• Rest of Latin America

Asia-Pacific

• India
• Japan
• China
• Australia
• South Korea
• Rest of Asia-Pacific

The Middle East & Africa (MEA)

• Gulf Cooperation Council (GCC)
• South Africa
• Rest of the Middle East & Africa