Protein Expression Market - Global Industry Size, Share, Analysis, Trends and Forecast 2022 - 2030
Select Access Type
The Global Protein Expression Market Size is valued at USD 2,739 million in 2021 and is estimated to achieve a market size of USD 7,421 million by 2030; growing at a CAGR of 11.8%.
Protein expression is a mechanism by which proteins in cells are modified, synthesized, and regulated. Protein expression is seen as an essential proteomic factor that enables the expression of recombinant proteins in various host systems. A host-cell-based functional requirement is used to synthesize and control proteins. Protein expression includes three processes such as transcription, translation, and post-translation modification. In addition, 3 methods are available for recombinant protein expressions including the synthesis of chemical protein, in-vivo expression of the protein, and in-vitro protein. For the development of new therapeutics with minimum side effects, biotechnology-based organizations are predominantly dependent on protein expression. Protein production is potentially a competitive market due to the rising prevalence of various drug-resistant diseases and increasing government funding for the development of biotechnology related medicines.
Global Protein Expression Market DRO’s:
Market Drivers:
- Increasing prevalence of chronic disorders
- Rising demand for protein biologics
- Growth in the life science and biopharmaceutical industries
- Surge in healthcare expenditure worldwide
Market Restraints:
- Stringent regulatory approval
- High cost of protein expression reagents and instruments
Market Opportunities:
- Rise in the pharmaceutical market in emerging regions
- Emergence of microfluidics
Report Coverage
| Market | Protein Expression Market |
| Market Size 2021 | USD 2,739 Million |
| Market Forecast 2030 | USD 7,421 Million |
| CAGR During 2022 - 2030 | 11.8% |
| Analysis Period | 2018 - 2030 |
| Base Year | 2021 |
| Forecast Data | 2022 - 2030 |
| Segments Covered | By Product and Services, By Application, By System Type, By End-User, And By Geography |
| Regional Scope | North America, Europe, Asia Pacific, Latin America, and Middle East & Africa |
| Key Companies Profiled | Bio-Rad Laboratories, Sigma-Aldrich Corporation, Agilent Technologies, Inc., Life Technologies Corporation, Takara Bio, Inc., Merck Millipore, QIAGEN, New England Biolabs, Inc., Promega Corporation, and GenScript Biotech Corporation. |
| Report Coverage |
Market Trends, Drivers, Restraints, Competitive Analysis, Player Profiling, Regulation Analysis |
| Customization Scope |
10 hrs of free customization and expert consultation |
Increased rates of geriatric populations, aging disorders, and the prevalence of chronic diseases, such as cancer are the factors that fuel the growth of the protein expression market. The growth of the protein expression market is driven by the increase in expenditures for protein research. High monetary inputs from the manufacture of protein goods will hinder market growth. In fact, the market is struggling by a major shortage of skilled health professionals and local expertise. Improvement in the protein-therapy market is also a primary source of developments, including mass spectrometry, advancements in molecular genetics as well as advancements in manufacturing techniques. In addition, rapid medical technological development, improved disease detection, and growth in healthcare in emerging markets should also have a positive impact on the market.
The number of suppliers to the market for protein expression is low, as the materials used for profiling and distributing proteins must comply with strict government regulations. Moreover, the probability of potential competition is weak and the market bargaining capacity is strong. Many customers on the market give producers opportunities to grow their revenue in the market.
Protein Expression Market Segmentation
The worldwide protein expression market is split based on product and service, system type, application, end-user, and geography.
Protein Expression Market By Product and Service
- Reagents
- Expression Vectors
- Competent Cells
- Instruments
- Services
Among all the products and services, the reagents segment accounted for the majority of the share during the forecast timeframe from 2022 to 2030. The high growth in the segment is owing to the widespread application of these products for research and biopharmaceutical manufacturing. Acids and bases, buffers, acrylamides, detergents, cell lysis of carbohydrates, protease inhibitors, general reagents, and solvents are some of the chemicals used in the protein expression process. On the other hand, the services segment is likely to achieve the fastest growth rate in the coming years.
Protein Expression Market By System Type
- Prokaryotic Expression Systems
- Mammalian Cell Expression Systems
- Insect Cell Expression Systems
- Yeast Expression Systems
- Others
According to our protein expression industry analysis, the prokaryotic expression systems segment is expected to lead the market with a significant share from 2022 to 2030. This technology leads the industry and provides several advantages over other protein expression techniques due to its large application, high production capacity, and inexpensive production. However, the mammalian cell expression systems segment is projected to showcase the highest growth rate during the study period from 2022 to 2030.
Protein Expression Market by Application
- Therapeutic Applications
- Industrial Applications
- Research Applications
According to our protein expression market forecast, the therapeutic application is the largest contributor among applications and is expected to continue its dominance in the coming years. Some of the factors such as rising preference for protein therapies to cure chronic disorders such as arthritis, diabetes, cancer, multiple sclerosis, anemia, and hemophilia, as well as increasing adoption of protein in biologics production are supporting the therapeutic application.
Protein Expression Market by End-User
- Pharmaceutical and Biotechnology Companies
- Academic Research Institutes
- Contract Research Organizations (CROs)
- Other
Pharmaceutical and biotechnology companies accumulated a significant market share in 2021 based on end-users due to rapid advancements in protein-based research, growing demand for biopharmaceuticals, and increased investment and support for medication design and development. Due to the increasing outsourcing by biotechnology and pharmaceutical companies for the development of new drugs and biologics, the contract research organization segment is anticipated to grow at the highest rate during the study period.
Protein Expression Market Regional Outlook
North America
- U.S.
- Canada
Europe
- U.K.
- Germany
- France
- Spain
- Rest of Europe
Latin America
- Mexico
- Brazil
- Rest of Latin America
Asia-Pacific
- India
- Japan
- China
- Australia
- South Korea
- Rest of Asia-Pacific
The Middle East & Africa (MEA)
- Gulf Cooperation Council (GCC)
- South Africa
- Rest of the Middle East & Africa
Increasing research focus on stem cells and cancer fuels the North America Protein Expression Market
North America is the largest main protein expression market followed by Europe. These regions dominate the global demand for the production of proteins due to factors such as the prevalence and continuous research and advancement of a well-established healthcare system. Asia-Pacific is the most rapidly expanding region in protein expression due to rising penetration into R&D activities in these areas by different biotechnologies and pharmaceutical giants. The rapid increase in health infrastructure and increasing awareness and, therefore, the need for biologics and other proteins in the region, are other key factors responsible for this region's rapid growth.
Protein Expression Market Players
Some of the key protein expression companies include Bio-Rad Laboratories, Sigma-Aldrich Corporation, Agilent Technologies, Inc., Life Technologies Corporation, Takara Bio, Inc., Merck Millipore, QIAGEN, New England Biolabs, Inc., Promega Corporation, and GenScript Biotech Corporation. In order to retain their competitiveness and market share, the industry leaders are launching innovative and technologically developed goods and solutions. For instance, the extension of RapTr cellular line production services to be used in CHO-GS cell lines was announced by Aragen Bioscience, Inc. in March 2018 using protein expression as well as research tools that offer versatility in cell line growth and high protein production.